Comparative Study of Albendazole and Oxfendazole in the Treatment of Cystic Echinococcosis in Sheep and Goats من كتب طب بيطرى
ABSTRACT
The objective of this study was to compare
the efficacy of albendazole and oxfendazole
in the treatment of cystic echinococcosis
using naturally infected sheep and goats.
Fifteen animals with natural infections of
cystic echinococcosis were randomly divid-
ed into 3 groups of 5 animals each. Two
groups were treated orally with either alben-
dazole or oxfendazole at 30 mg/kg body
weight twice a week for 4 weeks; a third
group served as controls. Ultrasound and
postmortem examination of the animals, as
well as microscopic examination of proto-
scoleces for eosin dye exclusion and flame
cell motility, were used to determine the
efficacy of the 2 drugs. Ultrasound examina-
tion revealed that 4 animals in the albenda-
zole group and 3 in the oxfendazole group
had decreased cyst viability (P < 0.05).
Intern J Appl Res Vet Med • Vol. 3, No. 2, 2005
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